Glossary
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X chromosome | A chromosome associated with sex determination. In most animals, the female has two, and the male has one X chromosome. [Wikipedia entry] |
X-inactivation | Leads to clumped chromatin termed Barr bodies, which are generally considered inert. [Wikipedia entry] |
X-linked alpha thalaasemia/mental retardation (ATR X) syndrome | Caused by mutations in the ATR X gene. ATR X syndrome is characterised by severe learning difficulties, a characteristic facial appearance, abnormal genitalia and alpha thalassemia. The ATR protein affects the 3D structure of chromatin in the nucleus. [Wikipedia entry] |
Xist | The gene responsible for X-inactivation. Xist makes a long RNA transcript that literally sticks along one of every pair of X-chromosomes switching most genes off. [Wikipedia entry] |
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