Azuara Lab Profile

Research Focus: Epigenetics, Development & Stem Cells

The long-term goal of our group is to unravel the chromatin characteristics that define pluripotency in embryonic stem (ES) cells versus somatic cell commitment. We are also investigating the epigenetic relationship between in vitro maintained ES cells versus the inner cell mass from which they are derived, to define the role of epigenetic silencing in the establishment and maintenance of pluripotency both in culture and in the embryo.